Immune Enhancement
Research on NAD+ (Nicotinamide Adenine Dinucleotide) and its connection to immune health, immune function, and immune-related diseases is an emerging field. NAD+ is essential for various aspects of immune function, particularly for immune cells.
Unlike other cells, immune cells don’t have a direct blood supply. They are produced in the bone marrow and move into the bloodstream to monitor for infections or abnormal cell growth.
To understand how NAD+ supports the immune system, you can picture NAD+ as the fuel that powers immune cells, enabling them to patrol the body and defend against pathogens, much like a well-equipped coast guard. Without sufficient NAD+, immune cells struggle to function efficiently.
The recent COVID-19 outbreak has shown us that older people are far more affected by the novel coronavirus than children. This is partly due to age-related decline in immune function — a phenomenon called immunosenescence.
Younger individuals have more responsive and efficient immune cells, enabling their bodies to mount a quicker and more effective immune response. In contrast, older adults experience a reduction in immune cell functionality, making it harder for them to clear infections such as SARS-CoV-2.
NAD+ affects immune cells in multiple ways. The primary mechanism is by activating sirtuins (SIRT1 to 7). The seven human sirtuins play a significant role in the immune system and have broad-spectrum antiviral properties. Research from Princeton University reveals that by switching on sirtuins, NAD+ not only blocks viruses from entering cells but also blocks their ability to replicate. This double defense mechanism works against both DNA and RNA viruses.
Researchers in the USA explore the relationship between NAD+ levels and COVID-19 infections.
Research from the EU discusses how NAD+ levels affect coronaviruses and their ability to replicate.
NAD+ influences sirtuins, which play a key role in restricting viral replication of both DNA and RNA viruses. Princeton University discusses the pathways involved.
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These statements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease. These results are not typical. Individual results may vary.
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