NAD+

Anti-Aging - Brain Health - Energy

What is NAD+?

NAD+ (Nicotinamide Adenine Dinucleotide) is a vital coenzyme found in almost all living cells, derived from Vitamin B, and essential for sustaining life. It plays a key role in cellular regeneration and energy conversion, supporting critical processes like DNA repair, cell metabolism, and overall cell health.

As a naturally occurring compound, NAD+ is integral to maintaining the function of your brain, internal organs, and neurological systems. Emerging research suggests that increasing NAD+ levels may slow cellular aging and potentially help to prevent certain age-related diseases.

You can think of NAD+ as cornerstone of health. It is so fundamental that without it, life would not be possible.

What Does NAD+ Do?

NAD+ is a critical cofactor required to convert the food we eat into cellular energy (ATP), fueling hundreds of essential processes that keep cells healthy. These include supporting energy metabolism, repairing DNA, protecting cells from damage, promoting brain and cardiovascular health, and reducing inflammation. In essence, NAD+ plays a vital role in maintaining the health of your cells and integrity of your DNA, keeping you healthier for longer.

Energy Production - NAD+ helps your cells convert food into energy by acting as an electron transporter.

DNA Repair - A constant supply of NAD+ is needed for the activation of PARPs, which detect and repair damaged DNA.

Gene Expression - NAD+ increases sirtuin activity (superhero genes) which increases metabolism, decreases inflammation, extends cell life, and prevents neurodegeneration.

Enzyme Activity- NAD+ is used in processes such as metabolizing alcohol and converting lactate to pyruvate in the body.

Neurotransmitter - NAD+ is released from smooth muscle, neurosecretory cells, and brain synaptosomes for cell-to-cell communication.

InfiNADi NAD+ is now available for those interested in boosting NAD+ levels. A pharmaceutical grade NAD+ product (99.99% pure), InfiNADi NAD+ can be found in premium anti-aging and wellness clinics. Contact us today to learn more about InfiNADi NAD+ and start offering InfiNADi NAD+ therapy in your clinic.

Why is NAD+ Important?

Emerging research suggests that boosting NAD+ levels through supplementation may slow or even reverse aspects of cellular aging. Studies indicate that NAD+ may also help prevent or delay the onset of  certain age-related disorders, including neurodegenerative conditions, cardiovascular diseases, diabetes, and obesity.

Recent research published in well-respected peer-reviewed journals has outlined the importance of adequate NAD+ levels in the fight against aging. By enhancing metabolic health and addressing common age-related metabolic defects, NAD+ therapy holds potential for a wide range of therapeutic applications. 

While many of the studies are preliminary in nature, the findings have revealed numerous important functions of NAD+ in delaying the cellular aging process and protecting against age-related decline.

 

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NAD+ Anti-Aging Mechanisms:

Contributes to longer telomeres

Promotes DNA repair

Supports energy production

Promotes chromosome health

Enhances neurotransmitter levels

Activates sirtuins (superhero genes)

Boost immune-cell signaling

Potential Applications

Research on NAD+ therapy is still evolving, and further clinical studies are needed to confirm its full range of potential benefits. However, a large body of published research on NAD+ therapy has demonstrated clear clinical improvements in patients without adverse events. Based on the available scientific research, clinical interventions to boost NAD+ levels may provide benefits for:

Anti-Aging

Chronic Stress

Cognitive Impairment

Autoimmune Disease

Clinical Depression

Chronic Fatigue Syndrome

Addiction

Neurological Disorders – Alzheimer's & Parkinson’s

Cardiac & Vascular Disorders

Metabolic – Diabetes & Obesity

Immune Conditions – Viral Infections & Immune Failure

NAD+ Therapy May Suit Those Who Want to:

Extend lifespan and healthspan.

Increase energy levels and reduce fatigue.

Restore neurological function.

Prevent cognitive decline.

Restore muscle strength and function.

Support weight-loss programs.

Recover from addiction and substance abuse.

However, more research and large-scale clinical trials are needed to fully evaluate the therapeutic potential of NAD+ for all its possible applications. If you're considering NAD+ therapy, it's important to consult a healthcare professional before starting treatment.

How NAD+ Regulates Cellular Aging

World-renowned Harvard scientist Dr. David Sinclair discovered that declining NAD+ levels accelerate the aging process. His research revealed that sirtuins, often referred to as “superhero” genes, play a crucial role in regulating cellular aging. Sirtuins act like the “CEOs” of your cells, protecting DNA and managing cellular aging, but they require NAD+ to function.

With sufficient NAD+, sirtuins can activate protective pathways, repair DNA, and switch off genes linked to aging, promoting healthier, longer-living cells. By replenishing NAD+ levels, NAD+ therapy helps power your cells’ engines (mitochondria), boosting energy production, supporting cognitive function, and promoting longevity at the cellular level.

Why Is NAD+ Vital to Combat Aging?

Declining NAD+ Levels Are a Hallmark of Aging

Scientists recognize NAD+ as one of the body’s most critical molecules, yet its levels decrease significantly with age. Groundbreaking research has discovered that by middle age NAD+ levels drop to less than 50% of youthful levels, and by age 80, they can fall as low as 1-10%.

This decline impacts essential functions, including sirtuin activation and PARP activity, both of which are vital for brain function, neurological health, and cellular repair. Lower NAD+ levels are linked to neurodegeneration, memory loss, decreased energy, heart conditions, weight gain, infertility, and many other age-related issues.

Replenishing NAD+ levels can help restore the body’s optimal functioning and combat the effects of aging.

 
Related Videos
A Cure for Aging? Dr. David Sinclair at TEDxSydney 
Lifespan: Why We Age and Why We Don’t Have To by David Sincliar for ‘Talks At Google‘ 
Recent Studies

Dr. David Sinclair (Harvard) outlines the use of NAD+ for metabolic and cardiovascular diseases.

Discusses how NAD+ declines with age – 50% reduction in NAD+ levels by age 40.

Explains how NAD+ can help with vascular aging as the process is NAD+ dependent.

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These statements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease. These results are not typical. Individual results may vary.